Patterning of the embryonic forebrain
JLR Rubenstein, PA Beachy - Current opinion in neurobiology, 1998 - Elsevier
JLR Rubenstein, PA Beachy
Current opinion in neurobiology, 1998•ElsevierThe vertebrate forebrain is derived from the anterior neural plate, where anteroposterior,
dorsoventral and local patterning mechanisms specify regional identify. The recent
identification of genetic regulators of these processes has opened the way to elucidating
how the major forebrain regions (ie cerebral cortex, basal ganglia, thalamus, and
hypothalamus) are formed, and how molecular lesions in these processes cause human
birth defects.
dorsoventral and local patterning mechanisms specify regional identify. The recent
identification of genetic regulators of these processes has opened the way to elucidating
how the major forebrain regions (ie cerebral cortex, basal ganglia, thalamus, and
hypothalamus) are formed, and how molecular lesions in these processes cause human
birth defects.
The vertebrate forebrain is derived from the anterior neural plate, where anteroposterior, dorsoventral and local patterning mechanisms specify regional identify. The recent identification of genetic regulators of these processes has opened the way to elucidating how the major forebrain regions (i.e. cerebral cortex, basal ganglia, thalamus, and hypothalamus) are formed, and how molecular lesions in these processes cause human birth defects.
Elsevier