[HTML][HTML] Fasting and postprandial overproduction of intestinally derived lipoproteins in an animal model of insulin resistance: evidence that chronic fructose feeding in …
M Haidari, N Leung, F Mahbub, KD Uffelman… - Journal of Biological …, 2002 - ASBMB
Insulin-resistant states are characterized by hypertriglyceridemia, predominantly because of
overproduction of hepatic very low density lipoprotein particles. The additional contribution
of intestinal lipoprotein overproduction to the dyslipidemia of insulin-resistant states has not
been previously appreciated. Here, we have investigated intestinal lipoprotein production in
a fructose-fed hamster model of insulin resistance previously documented to have whole
body and hepatic insulin resistance, and hepatic very low density lipoprotein …
overproduction of hepatic very low density lipoprotein particles. The additional contribution
of intestinal lipoprotein overproduction to the dyslipidemia of insulin-resistant states has not
been previously appreciated. Here, we have investigated intestinal lipoprotein production in
a fructose-fed hamster model of insulin resistance previously documented to have whole
body and hepatic insulin resistance, and hepatic very low density lipoprotein …