Adoptive protection of the Mycobacterium tuberculosis-infected lung: dissociation between cells that passively transfer protective immunity and those that transfer …
IM Orme, FM Collins - Cellular immunology, 1984 - Elsevier
Adoptive transfer of protective immunity to an aerogenic infection with the facultative
intracellular bacterium Mycobacterium tuberculosis was mediated by a population of T cells
acquired in the spleens of donor mice at the height of the primary cell-mediated immune
response to an immunizing infection with M. bovis bacillus Calmette-Guerin. Successful
adoptive immunotherapy was ablated by prior exposure of immune donor cells to ionizing
radiation or by treatment of these cells with antibody raised against the Ly-2 marker. In …
intracellular bacterium Mycobacterium tuberculosis was mediated by a population of T cells
acquired in the spleens of donor mice at the height of the primary cell-mediated immune
response to an immunizing infection with M. bovis bacillus Calmette-Guerin. Successful
adoptive immunotherapy was ablated by prior exposure of immune donor cells to ionizing
radiation or by treatment of these cells with antibody raised against the Ly-2 marker. In …