CD39/NTPDase-1 activity and expression in normal leukocytes
ED Pulte, MJ Broekman, KE Olson… - Thrombosis research, 2007 - Elsevier
INTRODUCTION: CD39/NTPDase-1 is a cell surface enzyme expressed on leukocytes and
endothelial cells that metabolizes ATP to ADP and AMP. CD39 is expressed on numerous
different types of normal leukocytes, but details of its expression have not been determined
previously. METHODS: We examined CD39 expression and activity in leukocytes isolated
from healthy volunteers. Expression of CD39 on leukocytes was measured by FACS and
activity of CD39 in lymphocytes and neutrophils was determined by an enzymatic radio-TLC …
endothelial cells that metabolizes ATP to ADP and AMP. CD39 is expressed on numerous
different types of normal leukocytes, but details of its expression have not been determined
previously. METHODS: We examined CD39 expression and activity in leukocytes isolated
from healthy volunteers. Expression of CD39 on leukocytes was measured by FACS and
activity of CD39 in lymphocytes and neutrophils was determined by an enzymatic radio-TLC …