Predictive value of plasma HIV RNA level on rate of CD4 T-cell decline in untreated HIV infection
ContextPlasma human immunodeficiency virus (HIV) RNA level predicts HIV disease
progression, but the extent to which it explains the variability in rate of CD4 cell depletion is
poorly characterized. ObjectiveTo estimate the proportion of variability in rate of CD4 cell
loss predicted by presenting plasma HIV RNA levels in untreated HIV-infected persons.
DesignRepeated-measures analyses of 2 multicenter cohorts, comprising observations
beginning on May 12, 1984, and ending on August 26, 2004. Analyses were conducted …
progression, but the extent to which it explains the variability in rate of CD4 cell depletion is
poorly characterized. ObjectiveTo estimate the proportion of variability in rate of CD4 cell
loss predicted by presenting plasma HIV RNA levels in untreated HIV-infected persons.
DesignRepeated-measures analyses of 2 multicenter cohorts, comprising observations
beginning on May 12, 1984, and ending on August 26, 2004. Analyses were conducted …