Intrahepatic arterial infusion of chemotherapy: clinical results

DS Dizon, NE Kemeny - Seminars in oncology, 2002 - Elsevier
Approximately 60% of patients diagnosed with colorectal cancer (CRC) will go on to develop
hepatic metastases. Although surgical resection is the only curative modality, a majority will
not be able to undergo surgery. Alternative methods for treating this population have
focused on the feasibility of hepatic arterial infusion (HAI) of chemotherapy. Randomized
data in this field have been hampered due to small numbers of patients in some trials, or
crossover between groups. However, most trials have suggested an improvement in both …