Background Vitamin D deficiency may be involved in the development of atherosclerosis
and coronary heart disease in humans. Methods We assessed prospectively whether
plasma 25-hydroxyvitamin D (25 [OH] D) concentrations are associated with risk of coronary
heart disease. A nested case-control study was conducted in 18 225 men in the Health
Professionals Follow-up Study; the men were aged 40 to 75 years and were free of
diagnosed cardiovascular disease at blood collection. The blood samples were returned …