Biology of the TRANCE axis
MC Walsh, Y Choi - Cytokine & growth factor reviews, 2003 - Elsevier
As the TNF and TNFR superfamilies have grown to more than two dozen combined
members over the past 30 years, their involvement in interactions between immune cells,
with regard to the events governing cellular differentiation, activation, and survival have
been well established. The recently identified TNF superfamily cytokine, TRANCE
(RANKL/OPGL/ODF/TNFSF11), which interacts with two receptors—one functional,
TRANCE-R (RANK/TNFRSF11A), and one decoy, OPG (TNFRSF11B)—is a survival factor …
members over the past 30 years, their involvement in interactions between immune cells,
with regard to the events governing cellular differentiation, activation, and survival have
been well established. The recently identified TNF superfamily cytokine, TRANCE
(RANKL/OPGL/ODF/TNFSF11), which interacts with two receptors—one functional,
TRANCE-R (RANK/TNFRSF11A), and one decoy, OPG (TNFRSF11B)—is a survival factor …