The pathological effects of immunosuppression of Schistosoma mansoni-infected mice, with particular reference to survival and hepatotoxicity after thymectomy and …
S Lucas, R Musallam, J Bain, O Hassounah… - Transactions of the …, 1980 - Elsevier
The effects of various immunosuppressive regimes on the survival and liver pathology of
mice infected with Schistosoma mansoni were investigated. T-cell deprivation before
infection (by adult thymectomy and subsequent anti-thymocyte serum administration), or
treatment with hydrocortisone or cyclo-phosphamide or azathioprine after infection, all
reduced survival of infected mice when compared with immunologically intact, infected mice.
T-cell deprivation or steroids produced severe liver damage in infected mice despite a …
mice infected with Schistosoma mansoni were investigated. T-cell deprivation before
infection (by adult thymectomy and subsequent anti-thymocyte serum administration), or
treatment with hydrocortisone or cyclo-phosphamide or azathioprine after infection, all
reduced survival of infected mice when compared with immunologically intact, infected mice.
T-cell deprivation or steroids produced severe liver damage in infected mice despite a …