[HTML][HTML] Wnts as retrograde signals for axon and growth cone differentiation

SJ Burden - Cell, 2000 - cell.com
Cell, 2000cell.com
Following neurogenesis and the initial steps of axon pathfinding, growth cones approach
their target cells and initiate the process of synapse formation. Much of our knowledge
regarding the mechanisms that regulate synapse formation arises from studies of
developing neuromuscular synapses. These studies suggest that presynaptic and
postsynaptic cells exchange signals that stimulate and coordinate their mutual differentiation
(
Following neurogenesis and the initial steps of axon pathfinding, growth cones approach their target cells and initiate the process of synapse formation. Much of our knowledge regarding the mechanisms that regulate synapse formation arises from studies of developing neuromuscular synapses. These studies suggest that presynaptic and postsynaptic cells exchange signals that stimulate and coordinate their mutual differentiation (
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