The prevailing neurocircuitry models of anxiety disorders have been amygdalocentric in
form. The bases for such models have progressed from theoretical considerations,
extrapolated from research in animals, to in vivo human imaging data. For example, one
current model of posttraumatic stress disorder (PTSD) has been highly influenced by
knowledge from rodent fear conditioning research. Given the phenomenological parallels
between fear conditioning and the pathogenesis of PTSD, we have proposed that PTSD is …