Antibiotic prophylaxis with azithromycin or penicillin for childhood-onset neuropsychiatric disorders
LA Snider, L Lougee, M Slattery, P Grant, SE Swedo - Biological psychiatry, 2005 - Elsevier
BACKGROUND: The acronym PANDAS (pediatric autoimmune neuropsychiatric disorders
associated with streptococcal infections) describes a subgroup of children with obsessive-
compulsive disorder and/or tic disorder that experience symptom exacerbations following
streptococcal infections. We hypothesized that the prevention of streptococcal infections
among children in the PANDAS subgroup would decrease neuropsychiatric symptom
exacerbations. METHODS: Twenty-three subjects with PANDAS were enrolled in a double …
associated with streptococcal infections) describes a subgroup of children with obsessive-
compulsive disorder and/or tic disorder that experience symptom exacerbations following
streptococcal infections. We hypothesized that the prevention of streptococcal infections
among children in the PANDAS subgroup would decrease neuropsychiatric symptom
exacerbations. METHODS: Twenty-three subjects with PANDAS were enrolled in a double …