[HTML][HTML] Association of a novel PDZ domain-containing peripheral Golgi protein with the Q-SNARE (Q-solubleN-ethylmaleimide-sensitive fusion protein (NSF) …
A Charest, K Lane, K McMahon… - Journal of Biological …, 2001 - ASBMB
PDZ domains are involved in the scaffolding and assembly of multi-protein complexes at
various subcellular sites. We describe here the isolation and characterization of a novel PDZ
domain-containing protein that localizes to the Golgi apparatus. Using an in silico cloning
approach, we have identified and isolated a cDNA encoding a ubiquitously expressed 59-
kDa protein that we call FIG. It is composed of two coiled coil regions, a leucine zipper, and a
single PDZ domain. Cytological studies using indirect immunofluorescence microscopy …
various subcellular sites. We describe here the isolation and characterization of a novel PDZ
domain-containing protein that localizes to the Golgi apparatus. Using an in silico cloning
approach, we have identified and isolated a cDNA encoding a ubiquitously expressed 59-
kDa protein that we call FIG. It is composed of two coiled coil regions, a leucine zipper, and a
single PDZ domain. Cytological studies using indirect immunofluorescence microscopy …