[HTML][HTML] A combination of caffeine, arginine, soy isoflavones, and L-carnitine enhances both lipolysis and fatty acid oxidation in 3T3-L1 and HepG2 cells in vitro and in …

S Murosaki, TR Lee, K Muroyama, ES Shin, SY Cho… - The Journal of …, 2007 - Elsevier
To develop an anti-obesity agent containing dietary components, we focused on the
mechanisms that enhance both lipolysis and fatty acid oxidation. Caffeine and arginine (CA),
a nonselective adenosine-receptor antagonist and an inducer of lipolytic hormone,
respectively, were used to stimulate lipolysis. Soy isoflavones and l-carnitine (SL),
stimulators of carnitine palmitoyl transferase 1A and a cofactor for β-oxidation of fatty acids,
respectively, were used to enhance fatty acid oxidation. Effects of a combination of CA and …