Vascular oxidative stress in Alzheimer disease

X Zhu, MA Smith, K Honda, G Aliev, PI Moreira… - Journal of the …, 2007 - Elsevier
Alzheimer disease and cerebrovascular dementia are two common causes of dementia and,
by present diagnostic criteria, are mutually exclusive using vascular pathology as an
arbitrary demarcation in differential diagnosis. However, evidence from epidemiological,
neuropathological, clinical, pharmacological, and functional studies suggest considerable
overlap in risk factors and pathological changes suggesting shared common pathogenic
mechanisms between these two diseases such that vascular factors play a vital role in the …