Effects of dexamethasone on the expression of myelin basic protein, proteolipid protein, and glial fibrillary acidic protein genes in developing rat brain
S Tsuneishi, S Takada, T Motoike, T Ohashi… - Developmental brain …, 1991 - Elsevier
Abstract Effects of dexamethasone (DEX) on the relative abundance of myelin basic protein
(MBP), proteolipid protein (PLP) and glial fibrillary acidic protein (GFAP) mRNAs in the
developing rat brain were examined. After DEX (1.0 mg/kg body weight) or saline was
administered intraperitoneally to 3-day-old rats for 7 consecutive days, wet weight, DNA
content and the relative abundance of the glia-specific mRNAs in cerebrum and cerebellum
were analyzed at postnatal days (P) 10, 20 and 30. DEX decreased both wet weight and …
(MBP), proteolipid protein (PLP) and glial fibrillary acidic protein (GFAP) mRNAs in the
developing rat brain were examined. After DEX (1.0 mg/kg body weight) or saline was
administered intraperitoneally to 3-day-old rats for 7 consecutive days, wet weight, DNA
content and the relative abundance of the glia-specific mRNAs in cerebrum and cerebellum
were analyzed at postnatal days (P) 10, 20 and 30. DEX decreased both wet weight and …