[HTML][HTML] MicroRNA expression dynamics during murine and human erythroid differentiation

M Zhan, CP Miller, T Papayannopoulou… - Experimental …, 2007 - Elsevier
OBJECTIVE: MicroRNAs (miRNAs) are an abundant class of small noncoding RNAs that
regulate diverse cellular functions by sequence-specific inhibition of gene expression. We
determined miRNA expression profile during erythroid differentiation and putative roles in
erythroid differentiation. METHODS: The expression profile of 295 miRNAs before and after
their erythroid differentiation induction was analyzed using microarray. Fluorescein-activated
cell sorting analysis was used to isolate mouse spleen erythroblasts at different …