RNA-dependent DNA polymerase in virions of Rous sarcoma virus.

HM Temin, S Mizutami - Nature, 1970 - cabdirect.org
HM Temin, S Mizutami
Nature, 1970cabdirect.org
Two independent groups of investigators found evidence of an enzyme in virions of RNA
tumour viruses which synthesizes DNA from an RNA témplate. This discovery, if upheld, will
have important implications not only for carcinogenesis by RNA viruses but abo for the
general understanding of genetic transcription; apparently the classical process of
information transfer from DNA to RNA can be inverted.
Abstract
Two independent groups of investigators found evidence of an enzyme in virions of RNA tumour viruses which synthesizes DNA from an RNA témplate. This discovery, if upheld, will have important implications not only for carcinogenesis by RNA viruses but abo for the general understanding of genetic transcription; apparently the classical process of information transfer from DNA to RNA can be inverted.
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