Age-related macular degeneration: etiology, pathogenesis, and therapeutic strategies

J Ambati, BK Ambati, SH Yoo, S Ianchulev… - Survey of …, 2003 - Elsevier
Age-related macular degeneration is the principal cause of registered legal blindness
among those aged over 65 in the United States, western Europe, Australia, and Japan.
Despite intensive research, the precise etiology of molecular events that underlie age-
related macular degeneration is poorly understood. However, investigations on parallel
fronts are addressing this prevalent public health problem. Sophisticated biochemical and
biophysical techniques have refined our understanding of the pathobiology of drusen …