[HTML][HTML] The human AC133 hematopoietic stem cell antigen is also expressed in epithelial cells and targeted to plasma membrane protrusions
The human AC133 antigen and mouse prominin are structurally related plasma membrane
proteins. However, their tissue distribution is distinct, with the AC133 antigen being found on
hematopoietic stem and progenitor cells and prominin on various epithelial cells. To
determine whether the human AC133 antigen and mouse prominin are orthologues or
distinct members of a protein family, we examined the human epithelial cell line Caco-2 for
the possible expression of the AC133 antigen. By both immunofluorescence and …
proteins. However, their tissue distribution is distinct, with the AC133 antigen being found on
hematopoietic stem and progenitor cells and prominin on various epithelial cells. To
determine whether the human AC133 antigen and mouse prominin are orthologues or
distinct members of a protein family, we examined the human epithelial cell line Caco-2 for
the possible expression of the AC133 antigen. By both immunofluorescence and …