[HTML][HTML] Dendritic cell subset ratio in peripheral blood correlates with successful withdrawal of immunosuppression in liver transplant patients
GV Mazariegos, AF Zahorchak, J Reyes… - American Journal of …, 2003 - Elsevier
Human dendritic cell (DC) subsets appear to play distinct roles in the induction and
regulation of immune responses. While monocytoid DC (DC1) induce T‐helper (Th) 1‐type
responses, plasmacytoid DC (DC2) have been reported to selectively induce Th2
responses. In blood, their precursors (p) can be identified as HLA‐DR+ lineage–cells that
are further characterized as CD11c+ CD123–/lo (IL‐3Rα–/lo)(pDC1) or as CD11c–CD123 hi
(pDC2) by rare event, flow cytometric analysis. We compared the incidences of pDC1 and …
regulation of immune responses. While monocytoid DC (DC1) induce T‐helper (Th) 1‐type
responses, plasmacytoid DC (DC2) have been reported to selectively induce Th2
responses. In blood, their precursors (p) can be identified as HLA‐DR+ lineage–cells that
are further characterized as CD11c+ CD123–/lo (IL‐3Rα–/lo)(pDC1) or as CD11c–CD123 hi
(pDC2) by rare event, flow cytometric analysis. We compared the incidences of pDC1 and …