[HTML][HTML] Normal high density lipoprotein inhibits three steps in the formation of mildly oxidized low density lipoprotein: step 1
M Navab, SY Hama, CJ Cooke… - Journal of lipid …, 2000 - ASBMB
Apolipoprotein AI (apoA-I) and an apoA-I peptide mimetic removed seeding molecules from
human low density lipoprotein (LDL) and rendered the LDL resistant to oxidation by human
artery wall cells. The apoA-I-associated seeding molecules included
hydroperoxyoctadecadienoic acid (HPODE) and hydroperoxyeicosatetraenoic acid
(HPETE). LDL from mice genetically susceptible to fatty streak lesion formation was highly
susceptible to oxidation by artery wall cells and was rendered resistant to oxidation after …
human low density lipoprotein (LDL) and rendered the LDL resistant to oxidation by human
artery wall cells. The apoA-I-associated seeding molecules included
hydroperoxyoctadecadienoic acid (HPODE) and hydroperoxyeicosatetraenoic acid
(HPETE). LDL from mice genetically susceptible to fatty streak lesion formation was highly
susceptible to oxidation by artery wall cells and was rendered resistant to oxidation after …