[HTML][HTML] The surface of lipid droplets is a phospholipid monolayer with a unique fatty acid composition

K Tauchi-Sato, S Ozeki, T Houjou, R Taguchi… - Journal of Biological …, 2002 - ASBMB
We found that caveolin-2 is targeted to the surface of lipid droplets (Fujimoto, T., Kogo, H.,
Ishiguro, K., Tauchi, K., and Nomura, R.(2001) J. Cell Biol. 152, 1079–1085) and
hypothesized that the lipid droplet surface is a kind of membrane. To elucidate the
characteristics of the lipid droplet surface, we isolated lipid droplets from HepG2 cells and
analyzed them by cryoelectron microscopy and by mass spectrometry. By use of
cryoelectron microscopy at the stage temperature of 4.2 K, the lipid droplet surface was …