Distribution characteristics of immunoglobulin-secreting cells in adenoids. Relationship to age and disease
D Nadal, N Soh, E Schläpfer, JM Bernstein… - International journal of …, 1992 - Elsevier
Forty-four adenoids and 52 palatine tonsils from 71 children and adolescents (age 3–21
years) undergoing surgery because of adenoidal hypertrophy or recurrent tonsillitis were
examined for the presence of immunoglobulin-secreting cells (ISC employing an enzyme-
linked immunospot assay (ELISPOT). ISC constituted less than 2% of the mononuclear cell
population. Adenoids contained IgG, IgA, and IgM ISC in significantly lower numbers than
palatine tonsils. The predominant isotype of the ISC was IgG, in adenoids accounting for …
years) undergoing surgery because of adenoidal hypertrophy or recurrent tonsillitis were
examined for the presence of immunoglobulin-secreting cells (ISC employing an enzyme-
linked immunospot assay (ELISPOT). ISC constituted less than 2% of the mononuclear cell
population. Adenoids contained IgG, IgA, and IgM ISC in significantly lower numbers than
palatine tonsils. The predominant isotype of the ISC was IgG, in adenoids accounting for …