[HTML][HTML] MicroRNA pathways in flies and worms: growth, death, fat, stress, and timing

V Ambros - Cell, 2003 - cell.com
V Ambros
Cell, 2003cell.com
Drosophila geneticists have uncovered roles for microRNAs in the coordination of cell
proliferation and cell death during development, and in stress resistance and fat metabolism.
In C. elegans, a homolog of the well-known fly developmental regulator hunchback acts
downstream of the microRNAs lin-4 and let-7 in a pathway controlling developmental timing.
Abstract
Drosophila geneticists have uncovered roles for microRNAs in the coordination of cell proliferation and cell death during development, and in stress resistance and fat metabolism. In C. elegans, a homolog of the well-known fly developmental regulator hunchback acts downstream of the microRNAs lin-4 and let-7 in a pathway controlling developmental timing.
cell.com