CSF levels of carnitine in children with meningitis, neurologic disorders, acute gastroenteritis, and seizure
M Shinawi, N Gruener, A Lerner - Neurology, 1998 - AAN Enterprises
M Shinawi, N Gruener, A Lerner
Neurology, 1998•AAN EnterprisesCarnitine concentrations in CSF, serum, and urine in normal febrile children and children
with meningitis, neurologic disorders, and dehydration were studied. Carnitine levels in CSF
were 1/10 compared with serum in normal febrile children. These levels increased two-to
threefold in the pathologic conditions studied. Since damage to the blood-brain barrier
occurs in these conditions, higher blood-brain barrier permeability might explain CNS
carnitine accumulation.
with meningitis, neurologic disorders, and dehydration were studied. Carnitine levels in CSF
were 1/10 compared with serum in normal febrile children. These levels increased two-to
threefold in the pathologic conditions studied. Since damage to the blood-brain barrier
occurs in these conditions, higher blood-brain barrier permeability might explain CNS
carnitine accumulation.
Carnitine concentrations in CSF, serum, and urine in normal febrile children and children with meningitis, neurologic disorders, and dehydration were studied. Carnitine levels in CSF were 1/10 compared with serum in normal febrile children. These levels increased two- to threefold in the pathologic conditions studied. Since damage to the blood-brain barrier occurs in these conditions, higher blood-brain barrier permeability might explain CNS carnitine accumulation.
American Academy of Neurology