Familial hyperpotassemia and hypertension accompanied by normal plasma aldosterone levels: possible hereditary cell membrane defect
Z Farfel, A Iaina, T Rosenthal, U Waks… - Archives of Internal …, 1978 - jamanetwork.com
Hypertension and hyperpotassemia that were accompanied by normal plasma aldosterone
and low renin levels and were responsive to chlorothiazide administration were found in a
29-year-old patient and two decades later in his 21-year-old son. Their renal function is
normal, including response to sodium sulfate, mannitol, and aldosterone infusions. Adrenal
insufficiency was excluded. The renin-aldosterone system was proved intact by
physiological and pharmacologic stress and angiotensin-II infusion. Also normal were …
and low renin levels and were responsive to chlorothiazide administration were found in a
29-year-old patient and two decades later in his 21-year-old son. Their renal function is
normal, including response to sodium sulfate, mannitol, and aldosterone infusions. Adrenal
insufficiency was excluded. The renin-aldosterone system was proved intact by
physiological and pharmacologic stress and angiotensin-II infusion. Also normal were …