Endothelial junctional protein redistribution and increased monolayer permeability in human umbilical vein endothelial cells isolated during preeclampsia
Y Wang, Y Gu, DN Granger, JM Roberts… - American journal of …, 2002 - Elsevier
Objective: To examine monolayer permeability and junctional protein distribution and
expression in endothelial cells isolated from women with preeclampsia and from women
with normal pregnancies. We hypothesized that increased endothelial monolayer
permeability in preeclampsia reflects altered monolayer barrier properties produced by
disorganization of endothelial cell junction proteins. Study Design: Endothelial cells were
isolated from umbilical veins from women with normal pregnancies (n= 9) and from women …
expression in endothelial cells isolated from women with preeclampsia and from women
with normal pregnancies. We hypothesized that increased endothelial monolayer
permeability in preeclampsia reflects altered monolayer barrier properties produced by
disorganization of endothelial cell junction proteins. Study Design: Endothelial cells were
isolated from umbilical veins from women with normal pregnancies (n= 9) and from women …