[HTML][HTML] Vascular permeability factor/vascular endothelial cell growth factor-mediated permeability occurs through disorganization of endothelial junctional proteins
CG Kevil, DK Payne, E Mire, JS Alexander - Journal of Biological Chemistry, 1998 - ASBMB
Vascular permeability factor/vascular endothelial growth factor stimulates endothelial
proliferation, angiogenesis, and increased vascular permeability in vivo. We investigated
mechanisms of vascular permeability factor-mediated endothelial monolayer permeability
changes in vitro.[14 C] Albumin flux across endothelial monolayers was measured following
a 90-min exposure to vascular permeability factor (660 pm). Vascular permeability factor
increased albumin flux to 3.4 times that of control albumin flux. Endothelial monolayers were …
proliferation, angiogenesis, and increased vascular permeability in vivo. We investigated
mechanisms of vascular permeability factor-mediated endothelial monolayer permeability
changes in vitro.[14 C] Albumin flux across endothelial monolayers was measured following
a 90-min exposure to vascular permeability factor (660 pm). Vascular permeability factor
increased albumin flux to 3.4 times that of control albumin flux. Endothelial monolayers were …