[HTML][HTML] Molecular cloning and characterization of UDP-GlcNAc: lactosylceramide β1, 3-N-acetylglucosaminyltransferase (β3Gn-T5), an essential enzyme for the …
A Togayachi, T Akashima, R Ookubo, T Kudo… - Journal of Biological …, 2001 - ASBMB
A new member of the UDP-N-acetylglucosamine: β-galactose β1, 3-N-
acetylglucosaminyltransferase (β3Gn-T) family having the β3Gn-T motifs was cloned from rat
and human cDNA libraries and named β3Gn-T5 based on its position in a phylogenetic tree.
We concluded that β3Gn-T5 is the most feasible candidate for lactotriaosylceramide (Lc 3
Cer) synthase, an important enzyme which plays a key role in the synthesis of lacto-or
neolacto-series carbohydrate chains on glycolipids. β3Gn-T5 exhibited strong activity to …
acetylglucosaminyltransferase (β3Gn-T) family having the β3Gn-T motifs was cloned from rat
and human cDNA libraries and named β3Gn-T5 based on its position in a phylogenetic tree.
We concluded that β3Gn-T5 is the most feasible candidate for lactotriaosylceramide (Lc 3
Cer) synthase, an important enzyme which plays a key role in the synthesis of lacto-or
neolacto-series carbohydrate chains on glycolipids. β3Gn-T5 exhibited strong activity to …