Neuropathologic features of amnestic mild cognitive impairment
RC Petersen, JE Parisi, DW Dickson… - Archives of …, 2006 - jamanetwork.com
Background The neuropathologic substrate of amnestic mild cognitive impairment (aMCI) is
not known. Objective To determine the neuropathologic features of patients who died while
their clinical classification was aMCI. Design Cohort study. Setting Community based.
Participants Sixty-six individuals, including 15 who had memory impairment beyond that
allowed for aging but who were not demented, were studied along with 28 clinically healthy
individuals and 23 patients with probable Alzheimer disease (AD) for comparison. Main …
not known. Objective To determine the neuropathologic features of patients who died while
their clinical classification was aMCI. Design Cohort study. Setting Community based.
Participants Sixty-six individuals, including 15 who had memory impairment beyond that
allowed for aging but who were not demented, were studied along with 28 clinically healthy
individuals and 23 patients with probable Alzheimer disease (AD) for comparison. Main …