Depression and C-reactive protein in US adults: data from the Third National Health and Nutrition Examination Survey

DE Ford, TP Erlinger - Archives of internal medicine, 2004 - jamanetwork.com
Background The biological mechanisms by which depression might increase risk of
cardiovascular disease are not clear. Inflammation may be a key element in the
development of atherosclerotic cardiovascular disease. Our objective was to determine the
association between major depression and elevated C-reactive protein (CRP) level in a
nationally representative cohort. Methods We estimated the odds of elevated CRP level (>
0.21 mg/mL) associated with depression in 6914 noninstitutionalized men and women (age …