Obesity-related disorders are closely associated with the pathogenesis of cardiovascular
disease. Adiponectin is a circulating adipose tissue-derived hormone that is down-regulated
in obese individuals. Hypoadiponectinemia has been identified as an independent risk
factor for type 2 diabetes, coronary artery disease, and hypertension, and experimental
studies show that adiponectin plays a protective role in the development of insulin
resistance, atherosclerosis, and inflammation. More recent findings have shown that …