[HTML][HTML] N-linked oligosaccharides on the low density lipoprotein receptor homolog SorLA/LR11 are modified with terminal GalNAc-4-SO4 in kidney and brain
D Fiete, Y Mi, EL Oats, MC Beranek… - Journal of biological …, 2007 - ASBMB
Sorting protein-related receptor (SorLA/LR11) is a highly conserved mosaic receptor that is
expressed by cells in a number of different tissues including principal cells of the collecting
ducts in the kidney and neurons in the central and peripheral nervous systems. SorLA/LR11
has features that indicate it serves as a sorting receptor shuttling between the plasma
membrane, endosomes, and the Golgi. We have found that a fraction of SorLA/LR11 that is
synthesized in the kidney and the brain bears N-linked oligosaccharides that are modified …
expressed by cells in a number of different tissues including principal cells of the collecting
ducts in the kidney and neurons in the central and peripheral nervous systems. SorLA/LR11
has features that indicate it serves as a sorting receptor shuttling between the plasma
membrane, endosomes, and the Golgi. We have found that a fraction of SorLA/LR11 that is
synthesized in the kidney and the brain bears N-linked oligosaccharides that are modified …