Ancylostoma caninum is a common canine parasite responsible for anemia and death in
infected dogs. Gene expression profiling was used to investigate molecular differences
between two different forms of the third larval stage (L3s): infective free-living larvae and in
vitro serum-stimulated larvae that mimic the initial stages of parasitism of a host. We
developed an A. caninum cDNA microarray consisting of 4191 EST clones, and used it to
identify a set of 113 genes that are differentially regulated between infective and parasitic …