[HTML][HTML] Bone mineral density loss and recovery during 48 months in first-time users of depot medroxyprogesterone acetate

MK Clark, MF Sowers, B Levy, S Nichols - Fertility and sterility, 2006 - Elsevier
OBJECTIVE: To compare changes in bone mineral density (BMD) during 48 months
between first-time depot medroxyprogesterone acetate (MPA) users, during use and after
discontinuation, to controls. DESIGN: Longitudinal study. SETTING: Academic community.
PATIENT (S): Women 18–35 years, newly initiating depot MPA (n= 178) and controls (n=
145) not using hormonal contraception. MAIN OUTCOME MEASURE (S): The BMD of the
hip and spine, measured at 3-month intervals, by dual energy roentgen absorptiometry …