[HTML][HTML] Differential antibody responses to Plasmodium falciparum glycosylphosphatidylinositol anchors in patients with cerebral and mild malaria
R Perraut, B Diatta, L Marrama, O Garraud… - Microbes and …, 2005 - Elsevier
Glycosylphosphatidylinositol (GPI) membrane anchors of Plasmodium falciparum surface
proteins are thought to be important factors contributing to malaria pathogenesis, and anti-
GPI antibodies have been suggested to provide protection by neutralizing the toxic activity of
GPIs. In this study, IgG responses against P. falciparum GPIs and a baculovirus recombinant
MSP1p19 antigen were evaluated in two distinct groups of 70 patients each, who were
hospitalized with malaria. Anti-GPI IgGs were significantly lower in patients hospitalized with …
proteins are thought to be important factors contributing to malaria pathogenesis, and anti-
GPI antibodies have been suggested to provide protection by neutralizing the toxic activity of
GPIs. In this study, IgG responses against P. falciparum GPIs and a baculovirus recombinant
MSP1p19 antigen were evaluated in two distinct groups of 70 patients each, who were
hospitalized with malaria. Anti-GPI IgGs were significantly lower in patients hospitalized with …