Complement deficiency states and infection: epidemiology, pathogenesis and consequences of neisserial and other infections in an immune deficiency
SC ROSS, P Densen - Medicine, 1984 - journals.lww.com
Serum proteins in the complement sequence play an important role in the generation of the
normal inflammatory response and in host defense against a wide variety of
microorganisms. Deficiencies of these proteins, either inherited or acquired, are associated
with an increased frequency of infections. The majority of the profound complement
deficiencies that have been reported are inherited abnormalities associated with either the
absence of the protein or the presence of a dysfunctional molecule. Deficiency syndromes …
normal inflammatory response and in host defense against a wide variety of
microorganisms. Deficiencies of these proteins, either inherited or acquired, are associated
with an increased frequency of infections. The majority of the profound complement
deficiencies that have been reported are inherited abnormalities associated with either the
absence of the protein or the presence of a dysfunctional molecule. Deficiency syndromes …