Fatty acid synthesis and its regulation
SJ Wakil, JK Stoops, VC Joshi - Annual review of biochemistry, 1983 - annualreviews.org
SJ Wakil, JK Stoops, VC Joshi
Annual review of biochemistry, 1983•annualreviews.orgThe biosynthesis of long-chain fatty acids occurs in two distinct steps. The first step is the
conversion of acetyl-eoA to malonyl-eoA, a reaction catalyzed by a biotin-containing
multienzyme system named acetyl-eoA carboxylase (Reaction 1). The second step
(Reaction 2) is the conversion of acetyl-eoA and malonyl-eoA to palmitate in the presence of
NADPH, a reaction catalyzed by the fatty acid synthetase (F AS).
conversion of acetyl-eoA to malonyl-eoA, a reaction catalyzed by a biotin-containing
multienzyme system named acetyl-eoA carboxylase (Reaction 1). The second step
(Reaction 2) is the conversion of acetyl-eoA and malonyl-eoA to palmitate in the presence of
NADPH, a reaction catalyzed by the fatty acid synthetase (F AS).
The biosynthesis of long-chain fatty acids occurs in two distinct steps. The first step is the conversion of acetyl-eoA to malonyl-eoA, a reaction catalyzed by a biotin-containing multienzyme system named acetyl-eoA carboxylase (Reaction 1). The second step (Reaction 2) is the conversion of acetyl-eoA and malonyl-eoA to palmitate in the presence of NADPH, a reaction catalyzed by the fatty acid synthetase (F AS).
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