Lung cancer is one of the most frequent causes of cancer-related death in the United States.
For patients with advanced non-small cell lung cancer (NSCLC), chemotherapy, alone or in
combination with radiation therapy, is considered the standard treatment. Although this
treatment may result in a modest improvement in patient survival, overall prognosis of these
patients remains dismal, and the treatment is nonspecific, nonselective, and toxic. Therefore,
new therapeutic strategies are needed. During the past decade, several molecules that …