Regulation of liver metabolism by the hepatic nerves

K Jungermann, A Gardemann, U Beuers… - Advances in enzyme …, 1987 - Elsevier
In the isolated rat liver perfused as usual via the portal vein, joint electrical stimulation of the
nerve fibers around the artery and the portal vein in the liver hilus increased glucose output,
shifted lactate uptake to output, decreased urea and glutamine formation as well as
ammonia uptake, reduced ketone body production, lowered oxygen uptake and reduced
perfusion flow simultaneously changing the intrahepatic flow distribution; it was
accompanied by an overflow of noradrenaline into the hepatic vein. All effects were …