[HTML][HTML] The link module from human TSG-6 inhibits neutrophil migration in a hyaluronan-and inter-α-inhibitor-independent manner
SJ Getting, DJ Mahoney, T Cao, MS Rugg… - Journal of Biological …, 2002 - ASBMB
TSG-6 protein (the secreted product of the tumor necrosis factor-stimulated gene-6), a
hyaluronan-binding protein comprised mainly of a Link and CUB module arranged in a
contiguous fashion, has been shown previously to be a potent inhibitor of neutrophil
migration in an in vivo model of acute inflammation (Wisniewski, HG, Hua, JC, Poppers, DM,
Naime, D., Vilcek, J., and Cronstein, BN (1996) J. Immunol. 156, 1609–1615). It was
hypothesized that this activity of TSG-6 was likely to be mediated by its potentiation of inter-α …
hyaluronan-binding protein comprised mainly of a Link and CUB module arranged in a
contiguous fashion, has been shown previously to be a potent inhibitor of neutrophil
migration in an in vivo model of acute inflammation (Wisniewski, HG, Hua, JC, Poppers, DM,
Naime, D., Vilcek, J., and Cronstein, BN (1996) J. Immunol. 156, 1609–1615). It was
hypothesized that this activity of TSG-6 was likely to be mediated by its potentiation of inter-α …