Idiopathic eosinophilic esophagitis is associated with a TH2-type allergic inflammatory response

A Straumann, M Bauer, B Fischer, K Blaser… - Journal of Allergy and …, 2001 - Elsevier
Background: Idiopathic eosinophilic esophagitis (IEE) is a chronic-inflammatory disorder of
the esophagus of unknown origin. The established cornerstone of diagnosis is a dense
infiltration of the esophagus with eosinophils, but neither the precise pattern of inflammatory
cell infiltration nor the mechanisms that likely contribute to induction and maintenance of the
inflammatory response have been described. Objective: The intention of this study was to
characterize the esophageal inflammatory infiltrate and the expression of cytokines in the …