Characterization of C5aR expression on murine myeloid and lymphoid cells by the use of a novel monoclonal antibody
A Soruri, S Kim, Z Kiafard, J Zwirner - Immunology letters, 2003 - Elsevier
The anaphylatoxin C5a is a potent proinflammatory stimulus with immunomodulatory
activities. Expression of its receptor C5aR (CD88) has been detected on cells of myeloid
origin such as granulocytes and monocytes/macrophages. However, controversial results
exist on the expression of C5aR on T and B lymphocytes as well as on mature dendritic cells
(DC). The aim of the present study was to characterize expression of C5aR protein on
myeloid and lymphoid cells in the mouse. For this purpose, rat monoclonal antibodies with …
activities. Expression of its receptor C5aR (CD88) has been detected on cells of myeloid
origin such as granulocytes and monocytes/macrophages. However, controversial results
exist on the expression of C5aR on T and B lymphocytes as well as on mature dendritic cells
(DC). The aim of the present study was to characterize expression of C5aR protein on
myeloid and lymphoid cells in the mouse. For this purpose, rat monoclonal antibodies with …