Sputum and bronchial submucosal IL-13 expression in asthma and eosinophilic bronchitis
MA Berry, D Parker, N Neale, L Woodman… - Journal of allergy and …, 2004 - Elsevier
BACKGROUND: Nonasthmatic eosinophilic bronchitis is a condition characterized by the
presence of eosinophilic airway inflammation in the absence of airflow obstruction or airway
hyperresponsiveness. In asthma, the TH2-type cytokine IL-13 has been implicated in the
development of airway inflammation and hyperresponsiveness. Whether the expression of
IL-13 is different between these 2 conditions is unknown. OBJECTIVE: We sought to
investigate whether IL-13 expression is increased in asthma compared with eosinophilic …
presence of eosinophilic airway inflammation in the absence of airflow obstruction or airway
hyperresponsiveness. In asthma, the TH2-type cytokine IL-13 has been implicated in the
development of airway inflammation and hyperresponsiveness. Whether the expression of
IL-13 is different between these 2 conditions is unknown. OBJECTIVE: We sought to
investigate whether IL-13 expression is increased in asthma compared with eosinophilic …