Common polymorphisms in the PPARγ2 and IRS-1 genes and their interaction influence serum adiponectin concentration in young Finnish men

F Mousavinasab, T Tähtinen, J Jokelainen… - Molecular genetics and …, 2005 - Elsevier
The Gly972Arg substitution of the insulin receptor substrate-1 (IRS-1) gene and the
Pro12Pro genotype of the peroxisome proliferator-activated receptor gamma 2 (PPARγ2)
gene have been suggested to be associated with type 2 diabetes mellitus. In this study, the
influence of these two polymorphisms on serum adiponectin concentrations was
investigated. The Pro12Ala polymorphism of the PPARγ2 gene and the Gly972Arg
polymorphism of the IRS-1 gene were genotyped in 252 young Finnish servicemen. The …