Fetal loss associated with excess thyroid hormone exposure
J Anselmo, D Cao, T Karrison, RE Weiss, S Refetoff - Jama, 2004 - jamanetwork.com
ContextMaternal hypothyroidism and hyperthyroidism have deleterious effects on the
outcome of pregnancy. While the effects of thyroid hormone (TH) deprivation on the fetus,
independently from that on the mother, can be studied in infants with congenital
hypothyroidism, this is not the case in those with fetal thyrotoxicosis. ObjectiveTo study the
effects of TH excess on fetuses carried by mothers with resistance to TH (RTH) who are
euthyroid despite high TH levels but who may carry normal fetuses that are exposed to high …
outcome of pregnancy. While the effects of thyroid hormone (TH) deprivation on the fetus,
independently from that on the mother, can be studied in infants with congenital
hypothyroidism, this is not the case in those with fetal thyrotoxicosis. ObjectiveTo study the
effects of TH excess on fetuses carried by mothers with resistance to TH (RTH) who are
euthyroid despite high TH levels but who may carry normal fetuses that are exposed to high …