Dietary regulation of stearoyl-CoA desaturase 1 gene expression in mouse liver.
JM Ntambi - Journal of Biological Chemistry, 1992 - ASBMB
Expression of the murine liver stearoyl-CoA desaturase gene (SCD1) is induced upon
feeding fasted mice a fat-free, high carbohydrate diet (Ntambi, JM, Buhrow, SA, Kaestner,
KH, Christy, RJ, Sibley, E., Kelly, TJ, and Lane, MD (1988) J. Biol. Chem. 263, 17291-
17300). In the present study, SCD1-specific RNA riboprobes and cDNA probes were used to
study the mechanism for the induction of SCD1 mRNA. Based on the time course of
induction, the SCD1 mRNA increased from 2-fold within 6 h to 45-fold within 36 h. Nuclear …
feeding fasted mice a fat-free, high carbohydrate diet (Ntambi, JM, Buhrow, SA, Kaestner,
KH, Christy, RJ, Sibley, E., Kelly, TJ, and Lane, MD (1988) J. Biol. Chem. 263, 17291-
17300). In the present study, SCD1-specific RNA riboprobes and cDNA probes were used to
study the mechanism for the induction of SCD1 mRNA. Based on the time course of
induction, the SCD1 mRNA increased from 2-fold within 6 h to 45-fold within 36 h. Nuclear …