[HTML][HTML] The transcription factors GATA4 and dHAND physically interact to synergistically activate cardiac gene expression through a p300-dependent mechanism

YS Dai, P Cserjesi, BE Markham… - Journal of Biological …, 2002 - ASBMB
An intricate array of heterogeneous transcription factors participate in programming tissue-
specific gene expression through combinatorial interactions that are unique to a given cell-
type. The zinc finger-containing transcription factor GATA4, which is widely expressed in
mesodermal and endodermal derived tissues, is thought to regulate cardiac myocyte-
specific gene expression through combinatorial interactions with other semi-restricted
transcription factors such as myocyte enhancer factor 2, nuclear factor of activated T-cells …