[HTML][HTML] Age-and irradiation-associated loss of bone marrow hematopoietic function in mice is reversed by recombinant human growth hormone

C Carlo-Stella, M Di Nicola, R Milani, P Longoni… - Experimental …, 2004 - Elsevier
OBJECTIVE: The aim of this story was to evaluate the activity of recombinant human (rh)
growth hormone (GH) in restoring bone marrow progenitor cell growth as well as cytokine-
elicited stem cell mobilization in aged BALB/c mice with impaired marrow hematopoietic
function and reduced stem cell mobilizing capacity. MATERIALS AND METHODS: BALB/c
mice included in this study were either naturally aged (group I) or aged after having been
used for radioprotective assays (group II). Mice were treated for 5 weeks with either rhGH …